Science at the Institute

Department of Morphological Sciences

Research carried out in the Department

Clinical anatomy of the cerebrospinal fluid outflow tract in small animals
Clinical and radiological anatomy of the skull cavity and the anterocervical junction in small animals
Morphology of the valve apparatus and heart vessels in domestic and wild mammals
Study of the functional morphology of the occlusal apparatus of carnivorous companion animals
Analysis of the morphology of selected bird species with the use of layer imaging techniques

Study of nuclear-cytoplasmic interactions due to the transfer of the nucleus to the cytoplasm of early embryo cells
Comparative histology of internal organs of domestic and wild animals.
Molecular and functional characteristics of cancer cells macroautophagy
Research on the development of metallic-polymer compositions and technology of producing layered nonwovens based on them with antimicrobial and filtering properties for sanitary products or medical protection.
Research on the anti-cancer effect of noble metal nanoparticles and carbon derivatives (graphene) on the growth and development of glioblastoma in studies based on the in ovo model
Research on the cytotoxicity of graphene in relation to connective tissue cells
Analysis of the content of selected biogenic elements and toxic metals in the tissues of free-living animals in relation to the health status of their local populations in Poland and the potential risk to game consumers
The use of biotechnology in the protection and preservation of the genetic material (germplasm) of the European bison ( Bison bonasus ).
Experimental animal embryology
Effect of heat shock on animal fertility

Department of Physiological Sciences

The most important research directions implemented at the Polish Financial Supervision Authority are:
a) stem cell biology,
b) regulation of the growth and development of animal organisms,
c) nutrition physiology and dietetics,
d) regulation of organ functions in physiological and pathological states and
e) veterinary immuno-oncology.

Department of Preclinical Sciences

Main topic: Diagnostics and pathomechanisms in infectious and invasive diseases, assessment of the impact of compounds that pollute the environment on the animal organism and development of experimental models of xenobiotics, alternative to animal studies

Department of Pathology and Veterinary Diagnostics

PATHOLOGY AND DIAGNOSTICS OF SELECTED INFECTIOUS AND INFECTIOUS ANIMALS.

The use of new methods in the diagnosis of animal diseases.

Diagnostics of functional disorders accompanying exercise in animals.

Pathophysiology of selected infectious and non-infectious diseases in animals.

Pathology of selected infectious and non-infectious diseases of animals with particular emphasis on neoplastic diseases.

Diagnostics, pathology and prevention of selected bird diseases

Pathology and diagnostics of selected infectious and non-infectious diseases of exotic, laboratory and non-domestic animals and fish

Pathology and diagnostics of selected honey bee diseases

Department of Food Hygiene and Public Health Protection

The laboratories of the Department of Food Hygiene and Public Health Protection operate in an internal program “Laboratory for the Diagnostics of Animal Risk Factors in Food of Animal Origin”. Research work is currently underway
in 8 thematic groups:

The occurrence of microbiological hazards in food of animal origin
Alternative food preservation methods (high hydrostatic pressure
and ionizing radiation) and prognostic microbiology
The prevalence of tuberculosis in wild and farm animals: molecular analysis of interspecies transmission and zoonotic potential; monitoring the health of the bison
The occurrence of parasitic threats in the food chain and the phenomenon of parasite resistance to drugs
Antimicrobial effect of nanomaterials – production hygiene and product safety (graphene, TiO photocatalytic coating₂ )
Assessment of the risk of contamination of products and production environment of food of animal origin with allergens

Genomic basics of milk production regulation in terms of milk hygiene
Analysis and interpretation of food law in the public health protection system, including natural disasters and the defense of food and feed against intentional contamination (bioterrorism, agroterrorism)

Department of Small Animal Diseases and Clinic

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Department of Large Animal Diseases and Clinic

Department of Animal Reproduction, Andrology and Reproductive Biotechnology

Research (main topics in the Department / Department)

Projects financed by the ERDF

Apparatus CB (Veterinary Research Center) Biomedical Research Center (CBB) implemented under the Regional Operational Program of the Mazowieckie Voivodeship 2007 – 2013 (RPO WM), project number RPMA.01.01.00-14-002 / 12, total project value 12 738 501, 83 PLN

Biomedical Research Center (CBB) implemented as part of the Regional Operational Program of the Mazowieckie Voivodeship 2007 – 2013 (RPO WM), project no. RPMA.01.01.00-14-007 / 15, total project value: PLN 37,297,272.75

Regenerative Medicine Center (CMR) implemented as part of the Regional Operational Program of the Mazowieckie Voivodeship 2014 – 2020 (RPO WM), project number RPMA.01.01.00-14-7874 / 17, total project value: PLN 87,875,830.21

Grants

Grant OPUS NCN: The role of proteins from the ALKBH family in the development of obesity and type 2 diabetes mellitus on the pig model implemented in cooperation with the Department of Molecular Biology of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences.

Grant Preludium 7 NCN: Mutations in the TP53 gene in a breast tumor in dogs and their clinical significance.

Grant Preludium NCN: Circulation mechanisms of iron ions from the decomposition of biodegradable ZnO nanoparticles doped with iron in the body.

Grant Miniatura 2 NCN: Assessment of the endometrosis process of mare endometrosis at the gene level.

Internal grant: Ferromagnetic nanoparticles for cancer diagnosis and therapy.

Internal grant: Determination of magnetic resonance sequences effective in imaging healthy and neoplastic tissues in mice with the use of new contrast agents based on nanoparticles.

Effect of repeated administration of fluoride-containing drugs on its concentration in tissues, serum and urine (cooperation with the Medical University of Warsaw, Prof. Leszek Pączek)

Assessment of the deposition of yttrium-90 microspheres (ceramic microspheres of polatom) after their intrahepatic, intraarterial administration in an animal model

Evaluation of the efficacy and safety of a device enabling independent ventilation of two patients using one ventilator in a large animal model

Influence of sexual maturity and hormonal stimulation on the function of ovarian follicles in gilts

Research directions

Study of the bioelectrical activity of the animal reproductive system in a pig model.

Pregnancy biomarkers in ruminants – PAG in the diagnosis of pregnancy in cattle.

Profiling of gene expression in (patho) reproductive physiology.

Collection, expansion and preparation of mesenchymal stem cells for therapeutic applications.

Profiling of mutations and gene expression in cancer.

Research in the field of reproductive biotechnology. In vitro experiments are carried out on gametes and embryos, and in vivo with the use of laboratory rodent models.

Laboratory of Internal Medicine