Science at the Institute
Department of Morphological Sciences
Research carried out in the Department
- Clinical anatomy of the cerebrospinal fluid outflow tract in small animals
- Clinical and radiological anatomy of the skull cavity and the anterocervical junction in small animals
- Morphology of the valve apparatus and heart vessels in domestic and wild mammals
- Study of the functional morphology of the occlusal apparatus of carnivorous companion animals
- Analysis of the morphology of selected bird species with the use of layer imaging techniques
- Study of nuclear-cytoplasmic interactions due to the transfer of the nucleus to the cytoplasm of early embryo cells
- Comparative histology of internal organs of domestic and wild animals.
- Molecular and functional characteristics of cancer cells macroautophagy
- Research on the development of metallic-polymer compositions and technology of producing layered nonwovens based on them with antimicrobial and filtering properties for sanitary products or medical protection.
- Research on the anti-cancer effect of noble metal nanoparticles and carbon derivatives (graphene) on the growth and development of glioblastoma in studies based on the in ovo model
- Research on the cytotoxicity of graphene in relation to connective tissue cells
- Analysis of the content of selected biogenic elements and toxic metals in the tissues of free-living animals in relation to the health status of their local populations in Poland and the potential risk to game consumers
- The use of biotechnology in the protection and preservation of the genetic material (germplasm) of the European bison ( Bison bonasus ).
- Experimental animal embryology
- Effect of heat shock on animal fertility
Department of Physiological Sciences
The most important research directions implemented at the Polish Financial Supervision Authority are:
a) stem cell biology,
b) regulation of the growth and development of animal organisms,
c) nutrition physiology and dietetics,
d) regulation of organ functions in physiological and pathological states and
e) veterinary immuno-oncology.
Department of Preclinical Sciences
Main topic: Diagnostics and pathomechanisms in infectious and invasive diseases, assessment of the impact of compounds that pollute the environment on the animal organism and development of experimental models of xenobiotics, alternative to animal studies
Department of Pathology and Veterinary Diagnostics
PATHOLOGY AND DIAGNOSTICS OF SELECTED INFECTIOUS AND INFECTIOUS ANIMALS.
The use of new methods in the diagnosis of animal diseases.
Diagnostics of functional disorders accompanying exercise in animals.
Pathophysiology of selected infectious and non-infectious diseases in animals.
Pathology of selected infectious and non-infectious diseases of animals with particular emphasis on neoplastic diseases.
Diagnostics, pathology and prevention of selected bird diseases
Pathology and diagnostics of selected infectious and non-infectious diseases of exotic, laboratory and non-domestic animals and fish
Pathology and diagnostics of selected honey bee diseases
Department of Food Hygiene and Public Health Protection
The laboratories of the Department of Food Hygiene and Public Health Protection operate in an internal program “Laboratory for the Diagnostics of Animal Risk Factors in Food of Animal Origin”. Research work is currently underway
in 8 thematic groups:
- The occurrence of microbiological hazards in food of animal origin
- Alternative food preservation methods (high hydrostatic pressure
and ionizing radiation) and prognostic microbiology - The prevalence of tuberculosis in wild and farm animals: molecular analysis of interspecies transmission and zoonotic potential; monitoring the health of the bison
- The occurrence of parasitic threats in the food chain and the phenomenon of parasite resistance to drugs
- Antimicrobial effect of nanomaterials – production hygiene and product safety (graphene, TiO photocatalytic coating 2 )
- Assessment of the risk of contamination of products and production environment of food of animal origin with allergens
- Genomic basics of milk production regulation in terms of milk hygiene
- Analysis and interpretation of food law in the public health protection system, including natural disasters and the defense of food and feed against intentional contamination (bioterrorism, agroterrorism)
Department of Small Animal Diseases and Clinic
Research Areas
The main research focus of the Department is the study of advances in diagnostic capabilities and the improvement of conservative and surgical treatment methods for diseases in small animals.
Division of Internal Diseases:
Experimental nano-oncology research in selected neoplasms in dogs and cats, as well as epidemiology and diagnostics of infectious diseases in animals, with particular emphasis on infectious myocarditis and endocarditis.
Division of Surgery:
Advancement and refinement of surgical treatment methods for diseases in small animals.
Reproduction Laboratory:
Development of modern diagnostic and therapeutic methods for pathological conditions of the reproductive system in small animals.
Department of Large Animal Diseases and Clinic
Division of Animal Reproduction, Andrology and Reproductive Biotechnology
Research (main topics in the Department / Department)
Projects financed by the ERDF
Apparatus CB (Veterinary Research Center) Biomedical Research Center (CBB) implemented under the Regional Operational Program of the Mazowieckie Voivodeship 2007 – 2013 (RPO WM), project number RPMA.01.01.00-14-002 / 12, total project value 12 738 501, 83 PLN
Biomedical Research Center (CBB) implemented as part of the Regional Operational Program of the Mazowieckie Voivodeship 2007 – 2013 (RPO WM), project no. RPMA.01.01.00-14-007 / 15, total project value: PLN 37,297,272.75
Regenerative Medicine Center (CMR) implemented as part of the Regional Operational Program of the Mazowieckie Voivodeship 2014 – 2020 (RPO WM), project number RPMA.01.01.00-14-7874 / 17, total project value: PLN 87,875,830.21
Grants
Grant OPUS NCN: The role of proteins from the ALKBH family in the development of obesity and type 2 diabetes mellitus on the pig model implemented in cooperation with the Department of Molecular Biology of the Institute of Biochemistry and Biophysics of the Polish Academy of Sciences.
Grant Preludium 7 NCN: Mutations in the TP53 gene in a breast tumor in dogs and their clinical significance.
Grant Preludium NCN: Circulation mechanisms of iron ions from the decomposition of biodegradable ZnO nanoparticles doped with iron in the body.
Grant Miniatura 2 NCN: Assessment of the endometrosis process of mare endometrosis at the gene level.
Internal grant: Ferromagnetic nanoparticles for cancer diagnosis and therapy.
Internal grant: Determination of magnetic resonance sequences effective in imaging healthy and neoplastic tissues in mice with the use of new contrast agents based on nanoparticles.
Effect of repeated administration of fluoride-containing drugs on its concentration in tissues, serum and urine (cooperation with the Medical University of Warsaw, Prof. Leszek Pączek)
Assessment of the deposition of yttrium-90 microspheres (ceramic microspheres of polatom) after their intrahepatic, intraarterial administration in an animal model
Evaluation of the efficacy and safety of a device enabling independent ventilation of two patients using one ventilator in a large animal model
Influence of sexual maturity and hormonal stimulation on the function of ovarian follicles in gilts
Research directions
Study of the bioelectrical activity of the animal reproductive system in a pig model.
Pregnancy biomarkers in ruminants – PAG in the diagnosis of pregnancy in cattle.
Profiling of gene expression in (patho) reproductive physiology.
Collection, expansion and preparation of mesenchymal stem cells for therapeutic applications.
Profiling of mutations and gene expression in cancer.
Research in the field of reproductive biotechnology. In vitro experiments are carried out on gametes and embryos, and in vivo with the use of laboratory rodent models.
Laboratory of Internal Medicine
Research directions
Research in the field of pathophysiology of horses and farm animals. The research includes, among others, research on the respiratory, digestive and circulatory systems using modern research methods. Study of the myoelectric activity in the digestive tract of ruminants on a sheep model.
Horse health monitoring program, preparation for exercise and post-exercise metabolic disorders
Analysis of the occurrence of mastitis caused by Staphylococcus aureus in a herd of dairy cows
Independent Department of Epidemiology and Veterinary Economics
Research (main areas of the division)
Epidemiology of diseases in livestock animals and horses.
Application of metabolomics in the diagnosis of animal diseases.
Modelling of the risk of occurrence of animal diseases.
Diagnosis and control of diseases in goats.
Epidemiology of anthelmintic resistance in goats.